NEW
Rx GLP-1 Protect + Repair Serum
Tailored Tretinoin
Formulated for the skin changes that can come with GLP-1 weight loss
$78 Trial Offer
Trial offer 2-month supply
Free Shipping
Free Shipping
200+ 5⭐ Reviews
GLP-1 Protect + Repair Serum is the very first serum formulated specifically for the skin changes that come from rapid GLP-1 therapy weight loss, with ingredients clinically studied to:
Visibly lift and firm sagging skin
Help restore a fuller, more defined facial appearance
Help reduce the appearance of fine lines and wrinkles
Restore and strengthen the skin's moisture barrier
Help skin renew and repair itself
How it works
After checkout, complete your Skin Profile, upload photos, and a board-certified doctor will review your information and prescribe your tailored formula (if applicable). No in-person office visit needed.
First trial bottle lasts 2 months and refills ship and bill every 3 months at $117. Pause, skip, or cancel anytime.
Tretinoin Face Prescription Online
First-time bottle lasts ~2 months. Refills last ~3 months and bill at $99/quarter. Change frequency or cancel anytime.
Enjoy the ease of an online dermatologist review and get your Tretinoin, a prescription strength retinoid online.
Bonus ingredient: Niacinamide, an anti-inflammatory healing compound that calms redness and boosts hydration.
Helps firm and lift sagging skin after GLP-1 weight loss. During rapid GLP-1 weight loss, fat beneath the skin can shrink faster than skin can adjust, making fine lines more visible. GLP-1 Protect + Repair Serum supports the skin's collagen to visibly smooth fine lines over time, for skin that looks firmer and more refined.
Helps rebuild facial volume and definition lost during GLP-1 weight loss. Rapid GLP-1 weight loss can shrink the natural fat pads in the cheeks, leaving the face looking less full. GLP-1 Protect + Repair Serum helps support the skin beneath the surface and plump it with moisture, for a softer, fuller look.
Helps support skin renewal slowed by GLP-1 therapy. Emerging research suggests GLP-1 medications may affect the cells involved in collagen production and repair. GLP-1 Protect + Repair Serum helps support the skin's natural renewal process, revealing fresher, smoother-looking skin.
Helps restore the skin barrier damaged by rapid weight loss. Research shows GLP-1 weight loss can leave skin thinner and less elastic, so it needs extra support. GLP-1 Protect + Repair Serum helps skin attract and hold moisture while defending against environmental stressors, keeping skin comfortable, hydrated, and resilient.
Key Ingredients
Tretinoin
During rapid GLP-1 weight loss, fat beneath the skin can shrink faster than skin can adjust, making fine lines and uneven texture more visible. Tretinoin, one of the most extensively studied prescription retinoids for skin aging, has been shown to stimulate collagen production and inhibit the enzymes that break it down, visibly smoothing fine lines and refining texture over time.
Hyaluronic Acid
When rapid GLP-1 weight loss reduces volume underneath, skin can look less plump, and fine lines show more easily. Hyaluronic Acid, a molecule naturally found in skin, draws in moisture and helps hold it there, helping plump the skin's surface for a smoother, more hydrated look.
Acetyl Hexapeptide-38
Rapid GLP-1 weight loss doesn't just happen in the body. The natural fat pads in the cheeks and under-eyes can shrink too, leaving the face looking less full. Acetyl Hexapeptide-38 is designed to support the natural fat cells beneath the skin, helping boost the look of soft, natural volume in the face.
Palmitoyl Tripeptide-38
As facial volume changes quickly during GLP-1 weight loss, skin relies on its internal framework of collagen and other support molecules to adapt. In lab studies, Palmitoyl Tripeptide-38, a collagen-supporting peptide, boosted six key components of that framework, for skin that looks smoother, with softened lines.
Base: ST-Elastomer 10, Q7-9120 Silicone Fluid, EL-7040 Hydro Elastomer Blend, Vitamin E Acetate, Liquid, Polyglycerol-3 Diisostearique
ALCOHOL FREE
CRUELTY FREE
FRAGRANCE FREE
PARABEN FREE
As easy as 1-2-3.
Get a tailored solution from our dermatologist partners to match your unique skin profile–gentle enough for even the most sensitive skin.
STEP 1
Share your skin goals
No need for an in-person dermatologist visit. In just a few minutes, share details about your skin and upload photos on our secure portal.
STEP 2
Our doctors tailor your formula
You are unique and your skin is too. A doctor will review your profile and tailor your formula.
STEP 3
Check in with your skin coach
Like any fitness routine, your formula will work best by starting out slowly. Your doctor is available at any time to check in and assess your progress.
Night Shift for anyone and everyone.
Whether you have sensitive or dry skin, or whether you’re a retinoid rookie or not, our Board-certified doctors got you. Understanding that everyone's skin is different, they provide you with an appropriate strength of our tailored Tretinoin prescription for your specific skin type.
At Dear Brightly we are committed to giving you a better overall retinoid experience.
ADD TO CARTAt Dear Brightly we are committed to giving you a better overall retinoid experience.
Start seeing results as early as 2 weeks.*
Practice makes progress! Start slowly, be patient, and watch your skin transform. Collagen isn’t built in a day, so we’ve made sure you’ve got the right routine for the journey. And we’re here to be your coach, teammate, and biggest fan – every step of the way.
*Individual results may vary
*Individual results may vary
1-2 weeks
Brightens and reduces uneven skin tone.
2-4 weeks
Discoloration is improved.
4-6 weeks
Brown spots diminish.
3-6 months
Reduced fine lines and wrinkles.
6 months - 1 year
Clear, radiant skin
The Power of Rx Retinoids.
Yes — when paired with ingredients like spironolactone and clindamycin, tretinoin can effectively address hormonal acne. This combination works by lowering excess oil production, targeting acne-causing bacteria, and calming inflammation. Together, these benefits lead to clearer skin, reduced redness, and a healthier overall complexion
Retinoids help your skin produce more collagen, which can reduce the look of fine lines and wrinkles. They also encourage the growth of new blood vessels, giving your complexion a healthy, rosy glow.
Retinoids help unclog the buildup around enlarged pores, making them look smaller and helping keep them clear over time.
Retinoids are one of the most effective ways to treat and prevent blackheads. They work by reducing clogged pores and the early stages of acne, helping minimize both inflammatory and non-inflammatory breakouts.
Persistent acne that resists standard treatments may benefit from topical tretinoin available via online prescription. By clearing clogged pores, retinoids enhance the skin’s ability to absorb other topical therapies.
Topical retinoids help exfoliate the skin, which supports the natural removal of milia. They also smooth rough texture by shedding dead skin cells and boosting glycosaminoglycan (GAG) production.
Retinoids aren’t a fix for all types of hyperpigmentation, but they can help fade freckles, melasma, sun spots, and dark marks by breaking up melanin clusters in the skin.
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